On behalf of everyone at Cancer Research UK, we were so sorry to hear of James’ death. He was a great champion of our work and we were delighted to meet with him several times, including welcoming him to The Francis Crick Institute to hear about our TRACERx research programme – a study we hope will transform our understanding of non-small cell lung cancer and take a practical step towards an era of precision medicine. James was hugely passionate about the importance of early detection and diagnosis of lung cancer – something we, at Cancer Research UK, will continue to push. Our thoughts are with James’ friends and family at this time. He will be greatly missed. Michelle Mitchell, CEO and Professor Charles Swanton, Chief Clinician, Cancer Research UK